SAMHSA’s updated Overdose Prevention and Response Toolkit provides

guidance to a wide range of individuals on preventing and responding to an overdose.

The toolkit also emphasizes that harm reduction and access to treatment

are essential aspects of overdose prevention. 

The toolkit, designed to augment overdose prevention and reversal

training, provides guidance on the role of opioid overdose reversal

medications, including naloxone and nalmefene, and how to respond

to an overdose. It also contains appendices for specific audiences,

including people who use drugs (PWUD), people who take prescription

opioids, first responders, healthcare practitioners, and others.